This resource provides a comprehensive overview of the 25 Equity and Practice Transformation milestones and their corresponding deliverables. It outlines each milestone’s requirements, submission cadence, dependencies, responsible submitting organization, and applicable submission cycle. The guide organizes milestones by program year and covers population health management capabilities, empanelment and access, data governance and implementation, care delivery models, behavioral and social health screening, value-based payment readiness, and key performance indicators. It also explains continued-participation requirements, final submission expectations, practice- and managed care plan-produced measures, KPI reporting requirements, performance thresholds, and the HEDIS-like measures associated with each population of focus. Practices can use this resource to plan deliverable development, understand sequencing requirements, and track progress toward milestone completion and payment eligibility.