These webinar slides share key findings and implementation guidance from the Depression Screening and Follow-Up Data Exchange Design Studio led by Connecting for Better Health and the PopHealth Learning Center. The session examines barriers that practices and health plans face when capturing depression screening results, documenting qualifying follow-up services, applying appropriate codes, and exchanging information across organizations. It also highlights practical strategies for improving workflows, reducing manual data entry, strengthening supplemental data submission, and ensuring completed screening and follow-up activities are reflected in DSF-E quality reporting. Practices, health plans, and data partners can use this resource to identify operational and data gaps and strengthen coordination across primary care, behavioral health, and quality-reporting systems.